Acute stridor is a sign of acute life-threatening airway compromise. Congenital malformations, life-threatening obstructions, acute infections, or anaphylaxis can cause stridor. Acute causes of stridor encompass conditions such as croup, bacterial tracheitis, epiglottitis, retropharyngeal abscess, foreign body aspiration, peritonsillar abscess, airway burns, and anaphylaxis. Here, we present 2 cases who presented with acute onset of persistent brassy cough and stridor later diagnosed with anaphylaxis presenting as spasmodic croup.