Synthetic Two-Components Skin Glue (Glubran Tiss) Effectiveness and Suitability in Pediatric Emergency Department

Cyanoacrylate skin glue is increasingly used as a non-invasive alternative to sutures. In pediatric Emergency Department (ED) the use of skin glue for superficial wound closure may offer many advantages over traditional wound closure devices related to reduction of pain, fast and easy application and better aesthetic results.

Objective: To assess effectiveness, suitability and tolerability of n-butyl 2 cyanoacrylate+2 octyl cyanoacrylate (synthetic skin glue Glubran Tiss, GEM, Viareggio, Italy) in selected wound repair in pediatric ED.

Methods: 31 children were enrolled in a prospective observational study on the use of the above skin glue for wound closure by ED operators. Enrolled patients were asked to return for a follow-up visit one week after the procedure.

Results: The skin glue under evaluation for wound closure showed to be effective and easy to use by the operators in all treated patients. No patient experienced pain; 1 patient experienced mild burning sensation after application.

Conclusions: Glubran Tiss skin glue wound closure in pediatric ED has shown to be suitable, effective and well tolerated by patient. This device is a valid alternative to surgical sutures for superficial wound closure in children.


Stefano Masi, Luca Mugnaini, Anna Pazzaglia, Claudia Saffirio, Anna Salvatore, Idanna Sforzi, Francesco Silenzi and Stefania Gianassi

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